The Melting Point M-565 for the automatic determination of melting and boiling points is designed for true, professional quality control. It includes a color display to observe the phase transition, is equipped with a video camera and a video replay function which allows reviewing the melting and boiling point determination. View more
Automated and reliable measurements


  • Fail-safe calibration with automated determination and storage of calibration results
  • Automatic determination of melting and boiling points
  • Highly accurate temperature regulation and measurement
  • Optimized reproducibility with homogeneous packing of the capillary using the Sample Loader M-569


  • Control of almost any type of sample by measuring melting point, boiling point or slip melting point.
  • Double check of difficult samples by comparing manual and automated measurement
  • Observation and replay of the phase transition using color display and video recording
  • Optional PC software for easy management of methods and results


  • Compliant with Pharmacopeia methods (European, USP, Japanese)
  • Comprehensive IQ/OQ procedures including certified calibration and verification compounds for GLP/GMP laboratories.
Video recording

Video recording

The video recording of the melting or boiling process enables a fatigue-proof, relaxed observation of the phase transition on the colour display in 6 fold magnification.    
Melting point video movie_01

Video movie

Video movie of every determination allows the look at the results after the measurement. Variable speed from single picture slow motion to fast motion up to 100x help to analyse the entire process in an efficient way.

Sample determination lens

Sample determination

Three different samples can be determined simultaneously. The user watches the samples on the display panel through a 2.5 magnifying glass for precise determination, detects the start and completion of melting and stores the values by pressing a button. The optimized design of the heating block allows faster cooling times and as a result a higher throughput per hour.
Heating block

Heating block

Optimized design of the heating block allows faster cooling times and therefore higher samples throughput per hour.  


A brilliant large colour display with a high resolution guarantees a comfortable control of the instrument and helps you to determine melting points in a most efficient way.  
Melting point calibration_02


Fully menu guided calibration in combination with the BUCHI Calibration Standards enable high quality calibrations.

Sample Loader M-569

For fast and efficient loading of samples into BUCHI melting Point capillaries.  
Printer and keyboard

Printer and Keyboard

The optional Printer is for GLP/GMP-conform documentation of results of calibration, melting and boiling point determination. The optional Keyboard can be used for a fast input of sample parameters. 
MeltingPoint Monitor Software

MeltingPoint Monitor Software

Optional MeltingPoint Monitor Software for an easy and save management of users, methods and results.  


Optional IQ/OQ Documentation for customers in a regulated environment. No need to create validation documents  
Expert Advice

What is the principle of the melting point detection on a M-565 Melting Point instrument?

The melting process is monitored using a reflection mode. A camera captures the images and when no change occurs anymore, the melting point is reached.

What is the accuracy of a melting point determination?

The accuracy of the melting point determined using a heating rate of 0.5 °/min is +/- 0.3 °C for measurements up to 250 °C. For measurements at higher temperatures the accuracy linearly changes from +/- 0.3 °C at 250°C to +/- 0.5 °C at 400 °C. 

How is a boiling point determined?

The boiling point is determined using the “Siwoloboff” method. The light beam illuminates the boiling point tube from the front and the camera records the image. The boiling point of the liquid has been reached when the flow of steam bubbles reaches a frequency of 0.6 Hz [Hertz].

Is it possible to measure the melting point of fats and waxes?

Fats and waxes are complex mixtures of several compounds. The melting point of waxes and fats is determined according to the slip melting point method. This can be done using the M-560 or M-565 Melting Point instrument (see the relevant application note).

What is the difference between the two measuring modes: according to Pharmacopeia or thermodynamic?

Pharmacopoeia vs thermodynamic_02
The determination according to Pharmacopeia measures the temperature at which the substance is completely melted. The thermodynamic method measures the temperature at which the sample starts to melt. Both melting points, the Pharmacopeia and the thermodynamic melting points, can be accurately determined by the BUCHI M-565. 

Are the calibration and verification sets certified?

Yes, the substances are traceable to a primary standard (LGC). All the certificates are included with the calibration and verification set. The calibration of the M-565 is performed using the pharmacopeia mode.

Is it possible to export the results to a LIMS software?

Yes, it is possible with the M-565 using the Melting Point Monitor software.


IQ/OQ Documentation

Installation/Operational Qualifications documentation often important when compiling with GMP/GLP.

Calibration Kit

Calibration Kit

Kit of four BUCHI certified standards for calibration of the Melting Point M-560 and M-565.


Melting Point Capillaries

The precision glass capillaries ensure highly reproducible melting point determinations.


Agate mortar and pestel

For homogenization of the sample. The polished surface is easy to clean, preventing cross-contamination.

Mini Keyboard

Mini keyboard

For convenient straightforward input of parameters.

Verification Kit

Verification kit

Kit of three BUCHI certified standards for verification of the Melting Point M-560 and M-565.


Software MeltingPoint Monitor

Software CD, Tutorial and single PC license. For installation under Windows 7 or Windows 8.

Repeating OQ

OQ Documentation

Repeating Operational Qualification to guarantee that the instrument meets predefined specifications.

Boiling point capillary and tube_01

Boiling point tube A Boiling point capillary B

The precision capillaries B generate perfect gas bubbles within tube A for reproducible boiling point determinations.


Sample Loader M-569

Instrument for fast and efficient loading of samples into melting point capillaries.



For documenting calibration results and melting and boiling point determinations.


P: 1300 552 003