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Flash Chromatography Separation and Preparative HPLC - Combined

prepchromWhat if there was a way to combine flash chromatography and preparative HPLC into a single platform that occupies a small footprint and allows you to process the entire purification process in your own laboratory, saving you both time and money?

BUCHI PrepChrom C-700 is an innovative chromatography system that fulfills this requirement with ease. The PrepChrom performs flash chromatography separation with preparative HPLC in one space saving system. If you face an increasing number of samples to purify and would like to perform the whole purification process in your own laboratory in order to speed up the analysis of isolated pure compounds, the PrepChrom could be the perfect solution for you.

With the PrepChrom, you don’t need multiple instruments. The system can completely purify any type of sample, from a few milligrams up to several hundred grams. A first flash separation allows collection of fractions, which can then be injected on an HPLC column to isolate the target compounds at a high purity. It features true quaternary gradient functionality and delivers accurate flow rates up to 250 mL/min at a pressure up to 100 bar (1450 psi). A significant reduction in processing times is the result, without any performance or quality loss.

Thanks to the intuitive graphical interface, you don’t even need to be an expert in chromatography. The user interface is interactive and simple to use. It guides you through the process, offering you the option to change parameters as you go. The PrepChrom interface also features powerful in-run interaction for fast optimisation of separations. The system can even run unattended.

The system comes with a range of great features, including:

  • True quaternary gradient functionality. The system can use up to four solvents at a time, with the flexibility to alter the parameters at any point
  • Fast optimisation of the flash separation thanks to software features, such as automatic gradient optimisation
  • Automatic collection of first flash separation fractions
  • Accurate flow rates up to 250mL/min at pressures of up to 100 bar (1450psi)
  • Isocratic elution and gradient elution
  • Automatic detection of compounds using the integrated UV detector together, with an optional Evaporative Light Scattering Detector for non-UV absorbing compounds
  • Detection automated fraction collection and automated system control
  • Easy connection of flash cartridges, glass columns or preparative HPLC columns. Any type of flash column, as well as preparative HPLC columns with a diameter up to 50mm filled with silica and a particle size down to 10µm
  • Delivers accurate flow rates up to 250 mL/min at a pressure up to 100 bar (1450 psi)
  • The ability to export data directly from the system via built-in USB ports

The new PrepChrom C-700 presents a significant reduction in processing times while delivering high performance results in one simple, user-friendly system.

Where can I find more information about the BUCHI PrepChrom C-700?

Visit Buchi or email or call 1300 552 003.

In Vitro Technologies is a scientific and medical company specialising in the distribution and support of scientific, clinical diagnostic and medical products. Please contact us for more information.